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JoVE Core
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JoVE Encyclopedia of Experiments
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癌症
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01:11 min
14.8: Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase
01:16 min
14.7: Pharmacogenetics of Drug Transporters: P-Glycoprotein and Solute Carrier Transporters
01:27 min
14.6: Pharmacogenetics of Phase II Enzymes: N-acetyltransferase, Thiopurine S-methyltransferase, UDP-glucuronosyltransferase
01:28 min
14.5: Pharmacogenetics of Phase I Enzymes: Cytochrome P450 Isozymes
01:27 min
14.4: Pharmacogenetics of Drug Metabolism: Overview
01:29 min
14.3: Pharmacogenetic Phenotypes: Alterations in Pharmacokinetics, Drug Targets and Biologic Milieu
01:27 min
14.2: Principles of Pharmacogenetics: Types of Genetic Variants
01:29 min
14.1: Pharmacogenetics and Pharmacogenomics: Overview
01:26 min
13.26: Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy
01:25 min
13.25: Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration
01:30 min
13.24: Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis
01:19 min
13.23: Modified-Release Drug Delivery Systems: Rate-Programmed II
01:25 min
13.22: Drug Dosing in Renal Diseases: Dose Adjustments Based on Drug Clearance and Elimination Rate Constant
01:28 min
13.21: Drug Dosing in Renal Diseases: Estimation of Glomerular Filtration Rate Based on Serum Creatinine Concentration
01:25 min
13.20: Drug Dosing in Renal Diseases: Measurement of Serum Creatinine Concentration and Clearance
01:25 min
13.19: Drug Dosing in Renal Diseases: Measurement of Glomerular Filtration Rate
01:08 min
13.18: Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment
01:22 min
13.17: Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test
01:14 min
13.16: Effect of Hepatic Disease on Pharmacokinetics: Active Drug, Metabolite and Fraction of Metabolized Drug
01:26 min
13.15: Effect of Hepatic Disease on Pharmacokinetics: Drug Dosing and Hepatic Blood Flow
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