Intracranial Implantation with Subsequent 3D In Vivo Bioluminescent Imaging of Murine Gliomas

作者：Mohammed G. Abdelwahab1, Tejas Sankar2, Mark C. Preul2, Adrienne C. Scheck1,2 1Neuro-Oncology Research,Barrow Neurological Institute of St. Joseph’s Hospital and Medical Center, 2Neurosurgery Research Laboratory,Barrow Neurological Institute of St. Joseph’s Hospital and Medical Center

简介：Intracranial implantation of GL261 cells into C57BL/6 mice produces malignant gliomas that recapitulate many of the hallmarks of human glioblastoma multiforme. We used GL261 cells stably expressing luciferase to allow us to use in vivo imaging to follow tumor progression. The surgery and 3D in vivo imaging are demonstrated.

标签: Intracranial Implantation, 3D In Vivo Bioluminescent Imaging, Murine Gliomas, GL261, Glioblastoma Multiforme, Intracranial Mouse Tumor Model, Firefly Luciferase, GL261-luc, GL261-luc2, C57BL/6-cBrd/cBrd/Cr Mice, Albino Variant, In Vivo Imaging, IVIS Spectrum, Caliper Life Sciences, Histological Features, Tumor Necrosis, Pseudopalisades, Neovascularization, Invasion, Hypercellularity, Inflammation,

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