简介：
Overview
This protocol enables clinical support staff in dermatology to process and store cutaneous tumor samples for research, minimizing disruption to clinical operations. It allows for the collection of excised tissues that are typically discarded, facilitating future biomedical research.
Key Study Components
Area of Science
- Dermatology
- Biomedical Research
- Clinical Protocol Development
Background
- Cutaneous tumors often discarded after Mohs micrographic surgery.
- Importance of preserving samples for research purposes.
- Need for protocols that integrate with clinical workflows.
- Potential for correlating biomarkers with patient outcomes.
Purpose of Study
- To enable the collection of cutaneous tumor samples for research.
- To ensure minimal impact on routine clinical operations.
- To facilitate future studies on protein and RNA biomarkers.
Methods Used
- Collection of excised tumor samples by medical assistants.
- Storage procedures designed for preservation of samples.
- Integration of sample collection into daily clinical practices.
- Collaboration between clinical staff and researchers.
Main Results
- Successful collection and preservation of cutaneous tumor samples.
- Establishment of a protocol that does not disrupt clinical workflow.
- Potential for future research correlating biomarkers with outcomes.
- Demonstration of the protocol by trained staff.
Conclusions
- Protocol allows for the effective use of discarded tissues for research.
- Can be adapted for use in various surgical practices.
- Enhances the potential for valuable biomedical research.
What types of tumors can be processed using this protocol?
The protocol is designed for cutaneous tumors such as squamous cell carcinoma, basal cell carcinoma, and melanoma.
Who demonstrates the protocol?
The protocol is demonstrated by Stefani Fawks, a Mohs histotechnician, and Dr. Mitchell Manway, a research fellow.
How does this protocol benefit clinical operations?
It allows for the collection of samples without interfering with routine clinical practices.
Can this protocol be adapted for other surgical practices?
Yes, with slight modifications, it can be applicable to any surgical practice that discards patient samples.
What is the main advantage of this protocol?
The main advantage is the preservation of excised tissues for research, which are typically discarded.
What outcomes can be correlated with the collected samples?
Correlations can be made between protein and RNA biomarkers in the tissue and plasma samples with patient outcome data.
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