Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death

作者： Sara Naranjo Gozalo1,2, Maria de los Angeles Ballesteros Sanz3, Carlos Alvarez De Arriba1, Victor Manuel Mora Cuesta4, Eduardo Miñambres García2,3, Laura Sánchez Moreno1 1Department of Thoracic Surgery and Lung transplant Unit,University Hospital Marqués de Valdecilla, 2University of Cantabria School of Medicine, 3Intensive Care Unit, Donor Coordination Unit,University Hospital Marqués de Valdecilla, 4Department of Pneumology, Lung Transplant Unit,University Hospital Marqués de Valdecilla

简介：

Overview

This protocol outlines a lung cooling rapid recovery technique combined with abdominal normothermic regional perfusion for organ procurement from controlled asystole donors. It is a safe and effective method to expand the donor pool.

Key Study Components

Area of Science

• Organ transplantation
• Donation after cardiac death
• Ischemic injury mitigation

Background

• Multi-organ recovery from controlled donation after cardiac death is complex.
• This method enhances outcomes for transplant recipients.
• It reduces ischemic damage due to hypotension and cardiac arrest.
• Effective management of donor conditions is crucial.

Purpose of Study

• To improve organ recovery techniques.
• To expand the donor pool safely.
• To minimize ischemic injury during the procurement process.

Methods Used

• Administer a bolus of Heparin intravenously to the donor.
• Prepare a sterile instrumentation table with necessary equipment.
• Set up a surgical field on the selected groin with disinfectant.
• Utilize electrocautery and suction systems during the procedure.

Main Results

• Demonstrated improved recovery outcomes for organ transplants.
• Showed reduced ischemic damage in donor organs.
• Validated the safety of the combined techniques.
• Expanded the potential donor pool effectively.

Conclusions

• The protocol is a viable option for organ procurement.
• It enhances the safety and efficacy of multi-organ recovery.
• Further studies may optimize the technique for broader application.

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