Surgical Technique for the Implantation of a Biomimetic Artificial Intervertebral Disc in a Goat Animal Model

作者： S. Amir Kamali1, Irin Kwananocha1,2, Celien A. M. Jacobs3, Koen Willemsen4,5, Marianna A. Tryfonidou1, Keita Ito3, Björn P. Meij1 1Department of Clinical Sciences, Faculty of Veterinary Medicine,Utrecht University, 2Research and Academic Service, Faculty of Veterinary Medicine,Kasetsart University, 3Orthopedic Biomechanics, Department of Biomedical Engineering,Eindhoven University of Technology, 4Department of Orthopedics,University Medical Center Utrecht, 53D Lab, Division of Surgical Specialties,Utrecht Medical Center Utrecht

简介：

Overview

This study presents a novel surgical technique for implanting a biomimetic artificial intervertebral disc called the BioAID. The method aims to restore cervical spine function using a goat model, showing promise for clinical applications in both human and canine patients.

Key Study Components

Area of Science

• Neurosurgery
• Biomechanics
• Orthopedics

Background

• Intervertebral disc degeneration can lead to cervical spine myelopathy.
• Current treatment options may not provide adequate stability or restoration of function.
• Biomimetic artificial discs offer a potential solution for disc replacement.
• This study explores a new surgical technique for implantation.

Purpose of Study

• To develop a reliable surgical method for implanting the BioAID.
• To assess the stability and placement accuracy of the artificial disc.
• To evaluate the potential for clinical application in various patient populations.

Methods Used

• Use of a goat model for in vivo implantation.
• Detailed surgical protocol including dissection and placement techniques.
• Fluoroscopy and computed tomography for imaging and verification.
• Assessment of disc placement and stability post-implantation.

Main Results

• The BioAID was accurately placed with immediate stability.
• Postoperative imaging confirmed proper alignment and restoration of disc height.
• Follow-up assessments showed maintained position of the artificial disc.
• The technique demonstrated secure fixation and rapid recovery.

Conclusions

• This novel surgical technique for BioAID implantation is promising.
• Future research will focus on long-term performance and tissue response.
• The study provides a foundation for further exploration of biomimetic discs.

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