This article discusses the research conducted by Mamed Toner at Massachusetts General Hospital, focusing on the applications of biomedical engineering in understanding blood cell physiology. The study aims to investigate the innate immune response and the regulation of inflammation without altering the natural state of the cells.
My name is Mamed Toner. I'm a trained in mechanical engineering originally and biomedical engineering and sciences afterwards. And I'm a faculty member at the Massachusetts General Hospital, Harvard Medical School, and Harvard, MIT, division of Health Sciences and Technology in exploring various applications of biomedical engineering in medicine, various from finding common cells in blood that can be, you can determine, find them very rapidly changing their physiology so you can understand the physiology of these cells in a disease state, let's say in inflammation or a burn or injured patient.
And trying to understand the innate immune system response and trying to understand how blood cells regulate the inflammatory response in these kind of cases and, and looking at their genomics and proteomics. In those kind of examples, what you want to do is say you like to find these cells without altering their physiology and expression levels and so and so forth. So what you're investigating is the natural physiology of the underlying problem and not an artifact of handling the cells.
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